Apply for Wholesale Access

Start saving with exclusive wholesale pricing for doctors, clinics, and spa partners.

Sign In to Your Wholesale Account

Manage your wholesale account and enjoy exclusive deals.

Unlock exclusive wholesale rates—apply now and save on premium packs!

Add your deal, information or promotional text

Syn-Ake: The powerful peptide that’s no joke

  • 2 min read

When you hear that a skincare ingredient mimics viper venom, you might think it’s an April Fool’s joke. But Syn-Ake is the real deal – a cutting-edge peptide that relaxes facial muscles to smooth expression lines and wrinkles. This ingredient is a star component of Dermasensa’s UP Ultra Peptide Serum, delivering noticeable anti-aging results without the need for injectables.

What is Syn-Ake?

Syn-Ake is a synthetic tripeptide designed to mimic the effects of Waglerin-1, a peptide found in the venom of the Temple Viper. Scientists developed this lab-created version to safely replicate the muscle-relaxing properties of the viper’s venom, without any of the harmful effects. The result? A groundbreaking skincare ingredient that helps reduce dynamic wrinkles and fine lines caused by repeated facial expressions.

How does Syn-Ake work?

The key to Syn-Ake’s effectiveness lies in its ability to temporarily block the receptors responsible for muscle contractions. Much like popular injectable treatments, Syn-Ake inhibits neuromuscular activity to relax facial muscles, reducing the depth of expression lines over time. What’s the difference? Syn-Ake works without paralyzing the muscles, allowing for a natural, youthful look with continued facial movement.

The Science behind the name

The name "Syn-Ake" is derived from "synthetic snake" because of its ability to replicate the effects of snake venom. While it may sound intimidating, this lab-created peptide is completely safe for topical use and has been extensively studied for its skin-smoothing benefits. Research has shown that consistent application of Syn-Ake can lead to a visible reduction in wrinkle depth, particularly in areas prone to repeated expressions, such as the forehead and around the eyes.

Syn-Ake in Dermasensa’s UP Ultra Peptide Serum

Dermasensa’s UP Ultra Peptide Serum is formulated with an impressive 22% patented peptide blend, including Syn-Ake. This powerhouse serum works on multiple levels to combat dynamic wrinkles by:

  • Relaxing facial muscles – By mimicking the effects of muscle-relaxing peptides, it helps smooth expression lines without freezing the face.

  • Lifting and tightening – The advanced peptide formula supports firmer, more contoured skin, reducing sagging over time.

  • Delivering visible results quickly – Many users notice improvements within 5-7 days, with continued enhancement over time.

While injectable wrinkle treatments remain popular, many people seek non-invasive alternatives that offer similar benefits. Syn-Ake provides a way to soften expression lines without the commitment, cost, or potential side effects of cosmetic procedures. Plus, it integrates seamlessly into your skincare routine, without having to make any appointments!

The truth behind the "Snake Venom" hype

It’s easy to see why some might think an ingredient inspired by viper venom is too wild to be true. But Syn-Ake has been extensively researched and praised for its ability to deliver real, visible improvements in wrinkle reduction. Unlike myths and gimmicks that flood the beauty industry, this peptide-backed technology is rooted in science, offering a serious alternative to more invasive anti-aging treatments.

So, while the idea of a snake-inspired skincare ingredient might sound like an April Fool’s prank, the benefits of Syn-Ake are anything but a joke. If you’re looking for a way to smooth wrinkles, relax facial muscles, and achieve firmer, younger-looking skin, it’s time to embrace the power of this innovative peptide – no syringe required!

Shop This Post

Shop This Post

Over time, dead cells build up, which can cause dullness, clogged pores, and uneven texture. By exfoliating regularly, you help your skin shed these dead cells, revealing a fresher, brighter complexion. There are two main types of exfoliation.

  • 3 min read

Take Dermasensa's quick two-step quiz and get your product recommendations to help you achieve radiant, healthy skin!

  • 2 min read

With Dermasensa’s high-performance formulas and a little daily commitment, 2025 can be the year you finally achieve your best skin yet.

  • 3 min read

Search